{"id":91215,"date":"2026-04-13T21:00:20","date_gmt":"2026-04-13T17:00:20","guid":{"rendered":"https:\/\/herecareers.com\/job\/head-of-early-asset-obu-international\/"},"modified":"2026-04-13T21:00:21","modified_gmt":"2026-04-13T17:00:21","slug":"head-of-early-asset-obu-international","status":"publish","type":"job_listing","link":"https:\/\/herecareers.com\/ar\/job\/head-of-early-asset-obu-international\/","title":{"rendered":"Head of Early Asset, OBU, International"},"content":{"rendered":"<p>411_3452063<\/p>\n<p><h3>Introduction To Role <\/h3>\n<p>Are you ready to turn breakthrough science into high impact launches across diverse markets, accelerating access for patients who need new options most? This role sits at the critical junction between discovery and delivery, converting mechanism of action, biomarkers and clinical profiles into clear, value\u2011maximizing pathways that work in the real world. You will lead how our earliest oncology assets progress from Phase\u202f2 decisions through registration and launch, shaping evidence, access and diagnostic strategies that reflect local standards of care and payer expectations. In a setting that empowers local ownership, you will bring entrepreneurial thinking to complex, fast\u2011moving environments, so that each decision advances both patient outcomes and business performance. <\/p>\n<h3>Accountabilities <\/h3>\n<ul>\n<li>Asset Strategy Ownership: Set the International Oncology asset strategy from Phase\u202f2 decision points through Phase\u202f3 and COMMID, translating mechanism of action, biomarker strategy and clinical profile into viable, value\u2011maximizing launch pathways by market archetype. <\/li>\n<li>Governance and Influence: Chair the International Oncology Early Asset forum and lead International input to GPTs; provide science\u2011based recommendations into ILT and support LSPC preparations on wave plans, indication sequencing and launch\/no launch propositions. <\/li>\n<li>Decision Frameworks: Own Oncology\u2011specific iLVA policy, criteria, and templates; define explicit no\u2011go thresholds and fast\u2011track pathways to enable timely, data\u2011driven decisions. <\/li>\n<li>Evidence Strategy and Trial Influence: Shape Phase\u202f3 and registration\u2011enabling program designs to reflect International standards of care, comparators, biomarker prevalence, and subpopulation needs; ensure PROs\/HRQoL and other endpoints align with HTA requirements. Co\u2011create and secure execution of an International evidence plan (including RWE, pragmatic studies, EAPs and post\u2011authorization commitments) to address payer and guideline decision drivers in priority markets. Also, anticipate and guide CMC and supply considerations; stability, shelf life, cold chain, pack\/label needs, critical to International launch feasibility. <\/li>\n<li>Market Access and Value Strategy: Co\u2011create pricing, access, and reimbursement strategies with Regional Market Access and HEOR; align on surrogate endpoint acceptance, indirect comparison needs and risk\u2011sharing constructs suitable for emerging and mature markets. Define the International value proposition and clinical narrative by tumor type and line of therapy; ensure payer\u2011ready evidence, economic models and value dossiers are available in line with wave plans. <\/li>\n<li>Companion Diagnostics Enablement: Co\u2011lead the International CDx strategy\u2014regulatory pathways, lab accreditation, assay availability and data integration; direct partnerships with diagnostic companies and lab networks to secure test availability aligned to launch. <\/li>\n<li>Risk Management and Decision Execution: Maintain a comprehensive risk register across clinical, regulatory, access, CDx, CMC and supply domains; assign owners and mitigation timelines, escalating trade\u2011offs to governance as needed. Conduct scenario planning and sensitivity analyses for wave plans and uptake assumptions; ensure assumptions are reflected in RBU\/QBR\/ABU planning and supply synchronization. <\/li>\n<li>International Cross\u2011Functional Leadership &#038; Capability Building: Lead the International Oncology Cross Functional Team (Commercial, Medical, Regulatory, Market Access\/HEOR, Diagnostics, CMC\/Supply, Finance, Digital); ensure clear accountabilities and delivery against iLVA and wave plan milestones. <\/li>\n<li>Portfolio Shaping and BD Integration: Evaluate Oncology BD\/licensing opportunities for International strategic fit, scientific differentiation and access feasibility; contribute to due diligence and integration planning. <\/li>\n<li>Therapy Area Strategy: Shape the International Oncology TA strategy with the VP OBU International, including investment prioritization, indication lifecycle planning and post\u2011launch optimization. <\/li>\n<\/ul>\n<h3>Essential Skills\/Experience <\/h3>\n<ul>\n<li>Advanced scientific qualification (MD, PhD, or PharmD; strong MSc with extensive Oncology leadership considered) <\/li>\n<li>Deep Oncology expertise with hands on impact on late\u2011stage strategy (solid tumours and\/or hematologic malignancies), including biomarker\/CDx strategy and evolving standards of care <\/li>\n<li>Proven senior leadership integrating science and commercial strategy to influence Phase\u202f3 design, evidence generation and access outcomes across multiple International markets <\/li>\n<li>Strong command of clinical data interpretation, comparative effectiveness, HEOR principles and RWE methods relevant to HTA\/payer decision making in Oncology <\/li>\n<li>Demonstrated influence at senior governance (GPTs, ILT; LSPC preparation) with a track record of securing alignment on complex, science driven trade\u2011offs <\/li>\n<li>Exceptional analytical and strategic skills to synthesize ambiguous data, run scenario planning and make decisive recommendations <\/li>\n<li>Extensive matrix leadership: directing cross functional, above country teams and coaching Oncology capabilities in diverse healthcare systems <\/li>\n<\/ul>\n<h3>Desirable Skills\/Experience <\/h3>\n<ul>\n<li>Above country leadership spanning both mature and emerging markets; familiarity with regulatory and HTA archetypes beyond US\/EU5 <\/li>\n<li>Experience scaling companion diagnostics (regulatory approvals, lab network enablement, quality systems, data\/reporting) <\/li>\n<li>Established networks with KEEs\/guideline contributors and experience with payer\/HTA scientific advice <\/li>\n<li>Experience assessing and integrating Oncology BD assets <\/li>\n<\/ul>\n<h3>Why AstraZeneca <\/h3>\n<p>Here your decisions directly shape how cutting\u2011edge oncology medicines reach patients sooner, with real ownership to adapt for local standards of care and payer needs. You will work at the forefront of a strong pipeline, leveraging big data and real\u2011world evidence while learning from colleagues across continents. <\/p>\n<p>If you are ready to convert science into scalable launches and shape the future trajectory of our oncology portfolio across diverse markets, take the lead and put your impact in motion today. <\/p>\n<h3>\u062a\u0627\u0631\u064a\u062e \u0627\u0644\u0625\u0639\u0644\u0627\u0646 <\/h3>\n<p>24-Mar-2026 <\/p>\n<h3>Closing Date <\/h3>\n<p>07-Apr-2026 <\/p>\n<p>AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry\u2011leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non\u2011discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. <\/p>\n<\/p>\n<p> #J-18808-Ljbffr<\/p>\n<p>2026-04-04 17:22:53<\/p>","protected":false},"author":100,"featured_media":0,"comment_status":"open","ping_status":"open","template":"","job_listing_type":[68],"job_listing_category":[1351],"job_listing_location":[720],"job_listing_tag":[],"class_list":["post-91215","job_listing","type-job_listing","status-publish","hentry","job_listing_type-full-time","job_listing_category-bio-pharmacology-health","job_listing_location-united-arab-emirates"],"metas":{"_job_featured_image":"","_job_featured":"","_job_filled":"","_job_urgent":"","_job_category":{"1351":"Bio &amp; Pharmacology &amp; Health"},"_job_type":{"68":"Full Time"},"_job_tag":[],"_job_expiry_date":"2026-06-18","_job_gender":"","_job_apply_type":"external","_job_phone":"","_job_apply_url":"https:\/\/en-ae.whatjobs.com\/coopob__cpl___411_3452063__3583?utm_source=3583&utm_medium=feed&keyword=Head-of-Early&location=Dubai&geoID=3","_job_apply_email":"","_job_salary_type":"","_job_salary":"","_job_experience":"","_job_career_level":"","_job_qualification":"","_job_video_url":"","_job_photos":"","_job_application_deadline_date":"2026-06-14","_job_address":"","_job_location":{"720":"United Arab Emirates"},"_job_map_location":{"address":"","latitude":"","longitude":""},"_job_logo":"https:\/\/herecareers.com\/wp-content\/uploads\/wp-job-board-pro-uploads\/_employer_featured_image\/2025\/11\/ICON-Here-Careers-Logo-150-150x150.png","_job_employer_name":"HR","_job_employer_url":"https:\/\/herecareers.com\/ar\/employer\/hr\/"},"cmb2":{"_job_careerjet_job_fields":{"_job_careerjet_detail_url":"","_job_careerjet_company_name":""}},"_links":{"self":[{"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing\/91215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing"}],"about":[{"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/types\/job_listing"}],"author":[{"embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/users\/100"}],"replies":[{"embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/comments?post=91215"}],"wp:attachment":[{"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/media?parent=91215"}],"wp:term":[{"taxonomy":"job_listing_type","embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing_type?post=91215"},{"taxonomy":"job_listing_category","embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing_category?post=91215"},{"taxonomy":"job_listing_location","embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing_location?post=91215"},{"taxonomy":"job_listing_tag","embeddable":true,"href":"https:\/\/herecareers.com\/ar\/wp-json\/wp\/v2\/job_listing_tag?post=91215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}